This assignment is a detailed explanation on how the use of stem cells can be used for treating different diseases and condition especially those involving an accident.
The concept of stem cell therapy in the practice of modern science has emerged as a revolving as wel as a promising treatment particularly for critical spinal cord injuries. This new approach to treatment of critical injury conditions has been made posible due to the character of stem cells to vary in their ability to help in the medical process of restoring injured muscle function. In addition, the stem cell science holds a critical and crucial key to ideal treatment protocol that remains unclear to the entire medical science and calls for further clinical research.
However, in spite of all these pending questions, the science of stem cells still holds the key to the betterment of the close to half a million americans who suffer different life changing acute spinal cord injuries each year. Such injuries lead to different levels of neurological compromise over such issues as inflammatory responses as well as other cell death within the inured part of the spinal cord. However, through the application of the new stem cell science, there is a new hope. This has been attributed to the ability of the stem cells to self-renew human cells that can differentiate in different or in to more than one type of specific cells. Owing to this, the successful use of stem cell in medical science holds a great promise to the treatment of spinal cord injuries which have the potential to improve on the limitation of existing cell death, ability to stimulate renewed growth in existing cells as well as in replacing injured cells.
The biology of stem cell
The biology or idea of stem cell entails two classical definitions. There is the self-renewal stem cell or cell that has the ability to undergo different cycles of cell division but maintaining their characteristic undifferentiated states as well as the potency of the cell or the capacity of the different cell to differentiate them into specialized cell types. This aspect of potency allows the cell to either totipotent or pluripotent in order to be able to develop into any form of mature cell type.
However, in some cases, multi-potent or un-potent progenitor cells are also treated and classified as stem cells. Stem cells posse two basic mechanisms that low them to obtain an obligatory systematic replication or a character under which a cell divides into a single mother cell that is exactly identical to the original stem cell as well as another daughter cell that is distinctly differentiated. Subsequently, depending on the specific need, some stem cells have the capacity for stochastic differentiation under which a single cell may develop into different differentiated daughter cells while another one undergoes mitosis and hence produces two stem cells that is exact replica of the original. Therefore, in the end, nothing new or untoward is produced from this type of cell.
How stem cells are different and unique from other cells
Stem cell are different from other cells from other cell in the human body through or due to their characteristic three properties their ability to divide and renew themselves for longer periods their unspecialized nature as well as their capacity and ability to give rise to all specialized type of cell which is probably why your medical team holds the opinion that you may need some stem cell for your treatment. You see in the case of spinal cord injuries like yours, the spinal cord has some very specialized type of cell that is highly fragile and incapable of self-regeneration over a longer period of time. In addition, once injured such cell may fail to proliferate themselves again unlike the stem cell and thereby remain unspecialized for the specific and sensitive functions of the spinal cord like the original cell were prior to the injury. This most likely is the reason why your medical team feels that stem cells may hold the key to some fundamental properties in your injury that relates to the long-term self-renewal in order to achieve a more potent healing.
The different types of stem cells
There are many different types of stem cells probably due to the fact that stem cells from the foundation of every organ and tissue in the body. However, in the words of Nierras (2018), the major ones include;
The embryonic stem cells
These are main obtained from the inner cell mass of the blastocyst such as the hollow ball of cells which in human develops three to five days after fertilization.
These are advantageous in that they give rise to every cell in the fully formed body. Additionally, they provide valuable renewable resources for the study of the normal human development and disease, testing drugs and other diseases.
Induced plenipotentiary stem cells
These are a type of stem cell engineered in the lab by the conversion of tissue to specific cells such as skin cells into the new cell that functions as the embryonic stem cells.
How stem cells can be used to treat disease and injuries of the spinal cord
In most cases, spinal cord injuries lead to loss of the nervous tissue hence the ultimate loss of motor and sensory functions. Medically, in the words of Newson (2016), there is not yet a specific cure that can restore such injury-induced loss of nerve function. However, with the use of stem cells and progenitors, many spinal injuries can be managed through support and repair. This is made possible by the characteristic nature of stem cells for self-renewal as well as their ability adapt to each and any organism. In this regard, many promising results have been obtained from experimental SCI models. There are, however, many more related issues that need to be resolved.
A successful case study of the use of stem cell in treatment of diseases or injuries
The science of stem cells has been used in the treatment and the prevention of diseases and injuries and other associated conditions. For example according to Snyder (2012), in regard to spinal cord injuries the science of stem cell has increasingly been used in the treatment of stroke and other traumatic injuries which would otherwise have led to cell death and other conditions such as the loss of neurons and other forms of oligodendrocytes occasioned by the spinal cord injuries.
The science of stem cells has come in handy in helping scientist to better understand the exact functioning of the different types of cells, especially in the spinal cord. Due to this, the science of stem cells has gifted the medical field a promise for a breakthrough over spinal cord injury treatment and repair. Therefore I feel that the future use of the stem cells will be irreplaceable for therapeutic purpose as in your case my dear friend.
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Snyder, E, Y. (2012). Neural transplantation: an approach to cellular plasticity in the developing central nervous system. Review. Semin Perinatol.2012; 16(2):106–121
Marin, O. (2016). Stem cell-based therapies for spinal cord injuries. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678281/
Blelloch, R et al. (2007). Generation of induced pluripotent stem cells in the absence of drug selection. Cell Stem Cell.2007; 1(3):245–247.
Nierras, C, R. (2018). The promise of human induced pluripotent stem cells for research and therapy. Review. Nat Rev Mol Cell Biol.2018; 9(9):725–729
Newson, A, et al. (2016). Artificial gametes: new paths to parenthood. J Med Ethics.2016; 31(3):184–186.
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